CDX Cell Lines

세포주 유래 이종이식 모델(CDX 모델) 사람 유래 종양세포를 마우스 피하에 이식한 in vivo 모델로, 효능 평가나 종양 연구에 활용할 있습니다. 항암제 비임상 연구에 가장 자주 활용되는 in vivo 모델 하나입니다.

젬파마텍은 췌장암, 유방암, 대장암, 폐암, 림프종 등의 방대한 CDX 세포주 컬렉션을 보유하고 있어, 이를 필요로 하는 다양한 약력학적 연구 유효성 평가에 대응할 있습니다. 이외에도 32종의 CDX 세포주를 Luciferase 발현하도록 변형하여, 생체발광을 통해 종양 용적을 비침습적으로 분석할 있습니다

Cancer TypeUnmodified Cell LineLuciferase-Tagged Cell Line
AdemocarcimomaCalu-3, NCI-H1666, NCI-H441,NCI-H1650
Acute Myeloid LeukemiaMOLM13, OCIAML3
Anaplastic CarcinomaCalu-6
Barett AdenocarcinomaOE33
Bladder CancerUM-UC-3, HT1376, RT4, T24, RT112/84
Brain CancerU251, U-87 MG
Breast CancerBT-20, BT-474, BT-549, HCC1937, HCC1954, HCC1569, Hs 578T, JIMT-1, MCF7, MDA-MB-175VII, MDA-MB-231, MDA-MB-436, MDA-MB-453, MDA-MB-468, SK-BR-3, HCC70, T47DMDA-MB-468-Luc, MDA-MB-231-Luc, MCF-Luc
Clear Cell CarcinomaEs-2
Colorectal CancerColo205, HCT-116, HT29, HT-55,  LoVo, LS174T, RKO, SW48
Colorectal Cancer; Dukes' Type CLs1034
Colorectal Cancer; Dukes' Type C, Grade IIISW948
Colorectal Cancer; Dukes' Type BSW480
Colon Cancer
HT-29-Luc, HCT116-Luc, RKO-Luc
Colon AdenocarcinomaCOLO-320
Duodenal CancerHuTu 80
Endometrial CarcinomaHEC-1-A
Gastric CancerHs 746T, MKN45, NCI-N87, SGC-7901, SNU-16, KATOIII, NUGC4
U251-Luc, U87 MG-Luc
LeukemiaHL-60, Jurkat, K562, MOLT-4, MV-4-11, Nalm-6, SUP-B15, THP-1, CCRF-CEM, Hut78, TF1, Hs 505.TNalm6-Luc, K562-Luc, MOLM 13-Luc, HL60-Luc, MV-4-11-Luc, Jurkat-Luc
Liver CancerHepG2, Huh7Huh7-Luc, HepG2-Luc
Lung Cancer
A549-Luc, NCI-H82, NCI-H2171
LymphomaU937, NK92, Jeko-1, Daudi, Ramos, JVM-2, KAPPAS 299, Raj, SU-DHL-10, SU-DHL-16, U-2932, L-540Raji-Luc, U-937-Luc, MM.1S-Luc, Jeko-Luc, Thp-1-Luc, Daudi-Luc, Ramos
MelanomaA375, COLO829, SK-MEL-28, SK-MEL-5A375-Luc
Multiple MyelomaNCI-H929, MM.1R, MOLP-8, RPMI-8226,  MM.1SRPMI8226-Luc
NeuroblastomaIMR-32, SK-N-BE(2)
NSCLCA549, HCC-827, NCI-H1703, NCI-H1755, NCI-H1975, NCI-H2122, NCI-H358, NCI-H460, NCI-H1299, NCI-H647
Ovarian CancerOVCAR-3, SK-OV-3, TOV-112DSKOV3-Luc, OVCAR-Luc
Pancreatic CancerAsPC-1, BxPC-3, CAPAN-1, CFPAC-1, HPAC, MIA PaCa-2, PANC-1, SW1990PANC-Luc
Prostate Cancer22RV1, LNCaP, PC-3, LNCaP C4-2B
Pulmonary Mucoepidermoid CarcinomaNCI-H226, NCI-H292, NCI-H727, NCI-H69
Renal CarcinomaACHN, 786-O
SarcomaHT1080, SJSA-1, U-2 OS
SCLCDMS-53, NCI-2171, NCI-H446, NCI-H526, NCI-H82, SHP-77
Skin CancerA431
Submandibular Adenosquamous CarcinomaA253
Squamous Cell CarcinomaFaDu
Tongue Squamous Cell CarcinomaCal 27
Uterine Cancer


GemPharmatech is committed to protecting and respecting your privacy, and we'll only use your personal information to administer your account and to provide the products and services you requested from us. From time to time, we would like to contact you about our products and services, as well as other content that may be of interest to you. If you consent to us contacting you for this purpose, please click below to say how you would like us to contact you:

In order to provide you with the content requested, we need to store and process your personal data. If you consent to us storing your personal data for this purpose, please click the checkbox below.

You can unsubscribe from these communications at any time. For more information on how to unsubscribe, our privacy practices, and how we are committed to protecting and respecting your privacy, please review our Privacy Policy.