Syngeneic Cell Lines

맞춤형 마우스 모델 제작
비임상 시험
바이오 분석 서비스표현형 분석 서비스항암제 유효성 평가Non-GLP Toxicity 독성평가대사성 질환에서의 유효성 평가자가면역질환에서의 유효성 평가신경퇴행성 질환에서의 유효성 평가세포 치료제 및 유전자 치료제 유효성 평가
무균(Germ-Free) 및 마이크로바이옴 플랫폼
Mouse-Derived Gut Microbiota LibraryCustomized Germ-free ServicesEvaluation of Anti-tumor Effect of Gut MicrobiotaMicrobiota Extraction and TransplantationGerm-free Rederivation and BreedingMicrobial Strain Culture and Colonization
맞춤형 세포주 서비스
Cell Line Customization ServicesSyngeneic Cell LinesReporter Cell LinesCDX Cell Lines
맞춤형 브리딩
Customized Mice Breeding ServicesCryopreservation and ResuscitationAssisted ReproductionMouse Rederivation Service
동물 품질 시험
SNP Testing ServicesMicrobiology Testing Services유전적 완전성Animal HealthAnimal Welfare
기타
Animal Facility and HusbandryReproductive and Embryology Services Isolation of Embryonic Fibroblasts

젬파마텍은 마우스 유래 세포 및 그 유전적 변형 세포와 더불어 PDL1, CD47, CD73, CD19, CD20, CD33, EGFR, HER2, BCMA 등 가장 흔히 활용되는 여러 표적 세포를 아우르는 방대한 동계 세포주 컬렉션을 보유하고 있어, 면역조절관문 약물의 효능 평가를 위한 다양한 종양 모델 자원을 제공하고 있습니다.


Cancer TypeCell LineBackgroundEngineered Human or Mouse TargetAvailability
ColorectalCT26BALB/chPDL1(Tg)-mPDL1(KO)Available
ColorectalCT26BALB/chCD47 (Tg)-mCD47(KO)Available
ColorectalCT26BALB/chPDL1(Tg)-mPDL1(KO)-hCD47(Tg)-mCD47(KO) Available  
ColorectalCT26BALB/chPDL1(Tg)-mPDL1(KO)-hCD73(Tg)-mCD73(KO) Available
ColorectalCT26BALB/chPDL1(Tg)-mPDL1(KO)-hCD39(Tg)-mCD39(KO)Available
ColorectalCT26BALB/chNectin4 (Tg)-mNectin4(KO)Available
ColorectalCT26BALB/chPDL1(Tg)-mPDL1(KO)-hB7H3(Tg)-mB7H3(KO)Available
ColorectalCT26BALB/chROR1(Tg)-mROR1(KO)Available
ColorectalCT26BALB/chPDL1(Tg)-mPDL1(KO)-hCD24A(CD24)(Tg)-mCD24A(CD24)(KO）Available  (Cell only)
ColorectalCT26BALB/chCD47(Tg)-mCD47(KO)-hCD24A(CD24)(Tg)-mCD24A(CD24)(KO）Available  (Cell only)
ColorectalMC38C57BL/6hPDL1(Tg)-mPDL1(KO)Available
ColorectalMC38C57BL/6hCD47 (Tg)-mCD47(KO)Available
ColorectalMC38C57BL/6hPDL1(Tg)-mPDL1(KO)-hCD73(Tg)-mCD73(KO) Available
ColorectalMC38C57BL/6hPDL1(Tg)-mPDL1(KO)-hB7H3(Tg)-mB7H3(KO)Available
ColorectalMC38C57BL/6hPDL1(Tg)-mPDL1(KO)-hCD24A(CD24)(Tg)-mCD24A(CD24)(KO)Available  (Cell only)
ColorectalMC38C57BL/6hCD47(Tg)-mCD47(KO)-hCD24A(CD24)(Tg)-mCD24A(CD24)(KO)Available  (Cell only)
BreastEMT6BALB/chPDL1(Tg)-mPDL1(KO)Available 
BreastEMT6BALB/chCD39(Tg)-mCD39(KO)Available
MelanomaB16F10C57BL/6hPDL1(Tg)-mPDL1(KO)Available
LiverH22BALB/chPDL1(Tg)-mPDL1(KO)-hCD47(Tg)-mCD47(KO) Available
LiverH22BALB/chPDL1(Tg)-mPDL1(KO) 
ColorectalCT26 BALB/cNoneAvailable
LiverH22BALB/cNoneAvailable
Breast4T1BALB/cNoneAvailable
BreastEMT6BALB/cNoneAvailable
LymphomaA20BALB/cNoneAvailable
LymphomaMPC-11BALB/cNoneAvailable
LymphomaJ558BALB/cNoneAvailable
B lymphocyteBcL1 clone 5B1bBALB/cNoneAvailable
RenalRENCABALB/cNoneAvailable
LeukemiaWEHI-3BALB/cNoneAvailable
Embryonal CarcinomaNFPEBALB/cNoneAvailable
ColorectalMC38 C57BL/6NoneAvailable
LungLLC1 C57BL/6NoneAvailable
PancreasPAN02 C57BL/6NoneAvailable
MelanomaB16F0C57BL/6NoneAvailable
MelanomaB16F1C57BL/6NoneAvailable
MelanomaB16F10C57BL/6NoneAvailable
BreastMMT 060562C57BL/6NoneAvailable
BreastE0771C57BL/6NoneAvailable
LymphomaYAC-1C57BL/6NoneAvailable
LymphomaE.G7-OVAC57BL/6NoneAvailable
LymphoblastC1498C57BL/6NoneAvailable
B lymphocyteHOPC 1F/12C57BL/6NoneAvailable
ProstateRM-1C57BL/6NoneAvailable
SarcomaSaI/NTBDNoneAvailable
BladderMB49TBDNoneAvailable


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