Syngeneic Cell Lines

젬파마텍은 마우스 유래 세포 및 그 유전적 변형 세포와 더불어 PDL1, CD47, CD73, CD19, CD20, CD33, EGFR, HER2, BCMA 등 가장 흔히 활용되는 여러 표적 세포를 아우르는 방대한 동계 세포주 컬렉션을 보유하고 있어, 면역조절관문 약물의 효능 평가를 위한 다양한 종양 모델 자원을 제공하고 있습니다.

Cancer Type	Cell Line	Background	Engineered Human or Mouse Target	Availability
Colorectal	CT26	BALB/c	hPDL1(Tg)-mPDL1(KO)	Available
Colorectal	CT26	BALB/c	hCD47 (Tg)-mCD47(KO)	Available
Colorectal	CT26	BALB/c	hPDL1(Tg)-mPDL1(KO)-hCD47(Tg)-mCD47(KO)	Available
Colorectal	CT26	BALB/c	hPDL1(Tg)-mPDL1(KO)-hCD73(Tg)-mCD73(KO)	Available
Colorectal	CT26	BALB/c	hPDL1(Tg)-mPDL1(KO)-hCD39(Tg)-mCD39(KO)	Available
Colorectal	CT26	BALB/c	hNectin4 (Tg)-mNectin4(KO)	Available
Colorectal	CT26	BALB/c	hPDL1(Tg)-mPDL1(KO)-hB7H3(Tg)-mB7H3(KO)	Available
Colorectal	CT26	BALB/c	hROR1(Tg)-mROR1(KO)	Available
Colorectal	CT26	BALB/c	hPDL1(Tg)-mPDL1(KO)-hCD24A(CD24)(Tg)-mCD24A(CD24)(KO）	Available (Cell only)
Colorectal	CT26	BALB/c	hCD47(Tg)-mCD47(KO)-hCD24A(CD24)(Tg)-mCD24A(CD24)(KO）	Available (Cell only)
Colorectal	MC38	C57BL/6	hPDL1(Tg)-mPDL1(KO)	Available
Colorectal	MC38	C57BL/6	hCD47 (Tg)-mCD47(KO)	Available
Colorectal	MC38	C57BL/6	hPDL1(Tg)-mPDL1(KO)-hCD73(Tg)-mCD73(KO)	Available
Colorectal	MC38	C57BL/6	hPDL1(Tg)-mPDL1(KO)-hB7H3(Tg)-mB7H3(KO)	Available
Colorectal	MC38	C57BL/6	hPDL1(Tg)-mPDL1(KO)-hCD24A(CD24)(Tg)-mCD24A(CD24)(KO)	Available (Cell only)
Colorectal	MC38	C57BL/6	hCD47(Tg)-mCD47(KO)-hCD24A(CD24)(Tg)-mCD24A(CD24)(KO)	Available (Cell only)
Breast	EMT6	BALB/c	hPDL1(Tg)-mPDL1(KO)	Available
Breast	EMT6	BALB/c	hCD39(Tg)-mCD39(KO)	Available
Melanoma	B16F10	C57BL/6	hPDL1(Tg)-mPDL1(KO)	Available
Liver	H22	BALB/c	hPDL1(Tg)-mPDL1(KO)-hCD47(Tg)-mCD47(KO)	Available
Liver	H22	BALB/c	hPDL1(Tg)-mPDL1(KO)
Colorectal	CT26	BALB/c	None	Available
Liver	H22	BALB/c	None	Available
Breast	4T1	BALB/c	None	Available
Breast	EMT6	BALB/c	None	Available
Lymphoma	A20	BALB/c	None	Available
Lymphoma	MPC-11	BALB/c	None	Available
Lymphoma	J558	BALB/c	None	Available
B lymphocyte	BcL1 clone 5B1b	BALB/c	None	Available
Renal	RENCA	BALB/c	None	Available
Leukemia	WEHI-3	BALB/c	None	Available
Embryonal Carcinoma	NFPE	BALB/c	None	Available
Colorectal	MC38	C57BL/6	None	Available
Lung	LLC1	C57BL/6	None	Available
Pancreas	PAN02	C57BL/6	None	Available
Melanoma	B16F0	C57BL/6	None	Available
Melanoma	B16F1	C57BL/6	None	Available
Melanoma	B16F10	C57BL/6	None	Available
Breast	MMT 060562	C57BL/6	None	Available
Breast	E0771	C57BL/6	None	Available
Lymphoma	YAC-1	C57BL/6	None	Available
Lymphoma	E.G7-OVA	C57BL/6	None	Available
Lymphoblast	C1498	C57BL/6	None	Available
B lymphocyte	HOPC 1F/12	C57BL/6	None	Available
Prostate	RM-1	C57BL/6	None	Available
Sarcoma	SaI/N	TBD	None	Available
Bladder	MB49	TBD	None	Available

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