Reporter Gene Cell Lines
젬파마텍은 Luciferase를 붙인 고형암 및 혈액암 세포주를 다수 보유하고 있어, 신규 항암제의 유효성 평가에 활용할 수 있는 다양한 종양 모델을 제공하고 있습니다. 이들 세포주의 특장점은 Luciferase를 태깅하였기에 이미징이 가능하다는 것입니다. 다시 말해, Luciferase-tag가 특정 기기 아래서 발광하기 때문에 암세포가 전이/발생할 때 이미징이 가능합니다.
| Types | Times |
| Humanized tumor cell line customization (One target) + in-vivo mouse tumorigenicity test | 3-4 months + 2 months |
| Gene knockout cell line customization + in-vivo mouse tumorigenicity test | 2-3 months + 2 months |
Transgene overexpression cell line customization (Including Reporter gene cell lines customization) + in-vivo mouse tumorigenicity test | 2-3 months + 2 months |
| Cancer Type | Cell Line | Availability |
| Leukemia | Nalm6-Luc | Available |
| THP-1-Luc | 2023 Q1 | |
| K562-Luc | Available (Cell only) | |
Jurkat-Luc | 2023 Q1 | |
| Liver Cancer | Huh7-Luc | Available |
| H22-Luc | Available | |
| HepG2-Luc | Available (Cell only) | |
| Colorectal Cancer | HT-29-Luc | Available |
| HCT116-Luc | Available | |
| Colon Cancer | RKO-Luc | Available |
| CT26-Luc | Available (Cell only) | |
| MC38-Luc | Available (Cell only) | |
| Glioblastoma | U251-Luc | Available |
| U87-Luc | Available | |
| Lymphoma | Raji-Luc | Available |
| jeko-1-Luc | 2023 Q1 | |
| 2PK-3-Luc | 2023 Q1 | |
| U937-Luc | Available | |
| A20-Luc | Available | |
| MOLM13-Luc | Available (Cell only) | |
| Lung Cancer | LLC1-Luc | Available |
| A549-Luc | Available | |
| Multiple Myeloma | RPMI8226-Luc | Available |
| Mouse Pancreatic Cancer | KPC-Luc | Available |
| Bladder Cancer | MB49-Luc | Available |
| Skin Cancer | A375-Luc | Available |
| Ovarian Cancer | SKOV3-Luc | Available (Cell only) |
| Breast Cancer | 4T1-Luc | Available (Cell only) |
| MDA-MB-231-Luc | Available (Cell only) | |
| MDA-MB-468-Luc | Available (Cell only) |